Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles

Beautiful paper from the Elling  and Zuber  Labs on a novel score to predict sgRNA efficiency. Also including a website for sgRNA design based on the VBC score: https://www.vbc-score.org/ . Brought to my attention by shared first author Julian Jude.

Paper: https://pubmed.ncbi.nlm.nih.gov/32514112/

Commentary: https://www.viennabiocenter.org/about/news/new-prediction-tool-sharpens-the-crispr-scissors/

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