Beautiful paper from the Elling and Zuber Labs on a novel score to predict sgRNA efficiency. Also including a website for sgRNA design based on the VBC score: https://www.vbc-score.org/ . Brought to my attention by shared first author Julian Jude.
Paper: https://pubmed.ncbi.nlm.nih.gov/32514112/
Commentary: https://www.viennabiocenter.org/about/news/new-prediction-tool-sharpens-the-crispr-scissors/
The Wermeling lab at the Karolinska Institutet 