• Studies of antibodies and T cells in patients with Rheumatic disease.
  • Novel potential drug targets in autoimmune disease; a role for IL-4R signaling.
  • Therapeutic antibody treatment for cancer; a role for different myeloid suppressor cells and IL-4R signaling.
  • Studies related to expansion, and CRISPR-based modification of hematopoietic stem cells.
  • Custom CRISPR/Cas9 screens to identify drug targets in inflammatory diseases and cancer.

Illustration: Marek Skupiniski

Outline CRISPR screen experimental setup:

crispr screen for homepage