Author: fredrikwermeling

Super interesting review by Braun et al!

https://www.nature.com/articles/s41596-022-00700-y

https://www.immunexut.org/top

A great resource for gene expression

Article –> https://www.sciencedirect.com/science/article/pii/S0092867421004293?via%3Dihub

https://bioicons.com/ with extensions for e.g. Incscape.

Another resource of free science illustrations: https://smart.servier.com/

A great achievement and milestone!

Super proud of the work by Vaishnavi Iyer developing antisense oligonucleotides to modulate T-cell activation. Great collaboration with labs at Karolinska Institutet and NTU, Singapore.

As always, the linked soundtrack: https://tinyurl.com/mr2avjs6

Paper: https://www.sciencedirect.com/science/article/pii/S0896841122000658

This award will allow us to continue and intensify our CRISPR-based studies to identify novel drug targets to overcome cancer drug resistance.

https://www.cancerfonden.se/forskning/for-forskare/samtliga-anslagsbeslut

We are super proud of this publication. See Twitter thread for more info: https://twitter.com/Wermeling_lab/status/1462857299073114119

https://pubmed.ncbi.nlm.nih.gov/34750099/

KI press release featured on the KI.se first page:

https://news.ki.se/new-findings-on-the-link-between-crispr-gene-editing-and-mutated-cancer-cells

Photo: Lotta Eriksson

Part of text written by Magdalena Lindén for “CMM news”:

The project “STUDIES OF NEUTROPHILS IN AUTOIMMUNE JOINT INFLAMMATION” was generously funded 2021-2024!

https://www.vr.se/soka-finansiering/beslut/2021-08-25-medicin-och-halsa.html

I’m delighted to share the work led by Yunbing Shen, with help from especially Long Jiang and Vaishnavi Iyer.

“A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system”

Paper: https://tinyurl.com/4sedjhtm

Linked soundtrack: https://tinyurl.com/5465m73y

CRISPR never generates a uniform genotype which complicates analyzing the targeted gene’s role without establishing clonal lines. Here we give examples of how the generated genetic heterogeneity can be leveraged for discovery –> RCC!

See Twitter threed for more info –> https://twitter.com/Wermeling_lab/status/1452537209320583173