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The Wermeling lab at the Karolinska Institutet

– Research related to Autoimmunity, Cancer immunotherapy, hematopoiesis, and CRISPR/Cas9

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CrispRGold – An impressive software!

–> http://crisprgold.mdc-berlin.de/

Published in:

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.

Chu VT, Graf R, Wirtz T, Weber T, Favret J, Li X, Petsch K, Tran NT, Sieweke MH, Berek C, Kuhn R, Rajewsky K.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12514-12519.

PMID: 27729526

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Author fredrikwermelingPosted on December 22, 2016December 22, 2016

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Recent Posts

  • The Immune Epitope Database!
  • We have deposited our favorite CRISPR screen plasmid @Addgene
  • Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles
  • I´ve made a new video about redundant and non-redundant genes in the CRISPR context
  • “Design and analysis of CRISPR-Cas experiments” by Hanna and Doench!
  • Collection of popular scientific texts/observations I have written in the past (in Swedish).
  • Our review “Designing custom CRISPR libraries for hypothesis-driven drug target discovery” is online!
  • Global Immunotalks!
  • Database with validated gRNAs from the Chari lab
  • Interesting study by Orange et al – PRIME Cells Predicting Rheumatoid Arthritis Flares

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