An interesting Cas9 competitor -Natronobacterium gregoryi Argonaute

PAM independent (!) cleavage using a 5´phosphorylated DNA (!) guide and Natronobacterium gregoryi Argonaute!

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DNA-guided genome editing using the Natronobacterium gregoryi Argonaute.

Gao F, Shen XZ, Jiang F, Wu Y, Han C.

Nat Biotechnol. 2016 May 2. doi: 10.1038/nbt.3547. [Epub ahead of print]

PMID: 27136078 link